HuagongsheHuagongshe Chemistry Print Report · For research reference only
tert-Butyl isocyanate → 3-[2-(trifluoromethyl)-4'-chlorobenzhydryloxy]-N-(tert-butyl)azetidine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | tert-Butyl isocyanate | HCID 62412 | — |
| Reactant | 3-[2-(Trifluoromethyl)-4'-chlorobenzhydryloxy]azetidine hydrochloride | HCID 68902463 | — |
| Product | 3-[2-(trifluoromethyl)-4'-chlorobenzhydryloxy]-N-(tert-butyl)azetidine-1-carboxamide | HCID 68902413 | — |
Reaction Steps
This material was prepared from 3-[2-(trifluoromethyl)-4′-chlorobenzhydryloxy]azetidine hydrochloride (98) (1.32 mmol) and tert-butyl isocyanate (1.32 mmol) using the procedure described for compound (10) (474 mg, 81%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504522B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-410c892c623047be80bc50bf5cc8f433 |
| Source note | uspto-grants-2009_03 |