HuagongsheHuagongshe Chemistry Print Report · For research reference only
Carbonate Ion → 3-[2-(trifluoromethyl)benzhydryloxy]-N-(tert-butyl)azetidine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Carbonate Ion | HCID 19660 | — |
| Reactant | tert-Butyl isocyanate | HCID 62412 | — |
| Reactant | 3-[2-(Trifluoromethyl)benzhydryloxy]azetidine hydrochloride | HCID 68905120 | — |
| Product | 3-[2-(trifluoromethyl)benzhydryloxy]-N-(tert-butyl)azetidine-1-carboxamide | HCID 11292673 | — |
Reaction Steps
This material was prepared from 3-[2-(trifluoromethyl)benzhydryloxy]azetidine hydrochloride (133) (0.33 mmol), tert-butyl isocyanate (0.33 mmol) and MP-carbonate (2.62 mmol/g, 0.98 mmol) using the procedure described for compound (10) (99.5 mg, 75%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504522B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-123aacc6a11444e495e5ac92cd1cec67 |
| Source note | uspto-grants-2009_03 |