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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785695Generated: November 2, 2026

4-Methylbenzaldehyde → p-Tolyl(2-(trifluoromethyl)phenyl)methanol

https://huagongshe.com/reaction/1785695

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-MethylbenzaldehydeHCID 7725—
Reactant(4-Chloro-2-(trifluoromethyl)phenyl)(phenyl)methanolHCID 68907806—
ReactantHCID 178506141HCID 178506141—
Productp-Tolyl(2-(trifluoromethyl)phenyl)methanolHCID 13309099—

Reaction Steps

This material was prepared from 2-(trifluoromethyl)phenylmagnesium bromide (16 mmol) and p-tolualdehyde (1.82 mL, 15 mmol) using the procedure described for compound (96) (4.28 g, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-d05f8651193c4d94b238cc07cd1ed39b
Source noteuspto-grants-2009_03