HuagongsheHuagongshe Chemistry Print Report · For research reference only
Cyclohexyl isocyanate → 3-[2-(trifluoromethyl)-4'-methylbenzhydryloxy]-N-(cyclohexyl)-azetidine-1-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Cyclohexyl isocyanate | HCID 18502 | — |
| Reactant | HCID 68902478 | HCID 68902478 | — |
| Product | 3-[2-(trifluoromethyl)-4'-methylbenzhydryloxy]-N-(cyclohexyl)-azetidine-1-carboxamide | HCID 11236190 | — |
Reaction Steps
This material was prepared from 3-[2-(trifluoromethyl)-4′-methylbenzhydryloxy]azetidine hydrochloride (151) (0.56 mmol) and cyclohexyl isocyanate (0.56 mmol) using the procedure described for compound (10). The desired product was obtained as a white foam (230 mg, 91%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504522B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-f98df0d88a7b4901896dc65308b2eb5a |
| Source note | uspto-grants-2009_03 |