反应详情

The corresponding hydrochloride salt was prepared from 1-benzhydryl-3-[2-(trifluoromethyl)-4′-methoxybenzyloxy]azetidine (156) (7.5 mmol) using the procedure described for compound (9). Due to the presence of impurities, the salt was partitioned between aqueous base and an organic solvent, the organic phase dried (MgSO4) and evaporated to afford the desired product as a colourless oil (730 mg, 29%).

1. customDue to the presence of impurities, the salt was partitioned between aqueous base
2. dry with materialan organic solvent, the organic phase dried (MgSO4)
3. customevaporated