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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1785706Generated: October 31, 2026

4-Fluorobenzaldehyde → (4-Fluorophenyl)[2-(trifluoromethyl)phenyl]methanol

https://huagongshe.com/reaction/1785706

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-FluorobenzaldehydeHCID 68023—
Reactant(4-Chloro-2-(trifluoromethyl)phenyl)(phenyl)methanolHCID 68907806—
ReactantHCID 178506141HCID 178506141—
Product(4-Fluorophenyl)[2-(trifluoromethyl)phenyl]methanolHCID 49963912—

Reaction Steps

This material was prepared from 2-(trifluoromethyl)phenylmagnesium bromide (16 mmol) and 4-fluorobenzaldehyde (1.64 mL, 15 mmol) using the procedure described for compound (96) (4.27 g, 100%).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07504522B2
Source datasetuspto-grants-2009_03
ORD IDord-37829da8c28c4383bf0640fbec818027
Source noteuspto-grants-2009_03