HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methylpiperazine → HCID 68904226, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methylpiperazine | HCID 53167 | — |
| Reactant | HCID 68906069 | HCID 68906069 | — |
| Reactant | HCID 68907467 | HCID 68907467 | — |
| Product | HCID 68904226 | HCID 68904226 | 67% |
Reaction Steps
3-[4-(4-methyl-piperazin-1-ylmethyl)phenyl-2-(trifluoromethyl)phenyl]methoxy-N-(tert-butyl)azetidine-1-carboxamide (211) was prepared using the procedure given in Example 146 for compound 196, starting from compound 195 and N-methylpiperazine. Purification through an SCX-2 cartridge afforded the title compound as a white solid (32 mg, 67% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07504522B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-c188ddcfad56499c8fe32d91046306f0 |
| Source note | uspto-grants-2009_03 |