3-Chloro-2-methylbenzenesulfonyl chloride → 3-Chloro-N-(2-ethyl-pyrimidin-4-yl)-2-methyl-benzenesulfonamide

HRID 1786127Notes

Reaction equation

HRID 1786127 reaction equation
[CH2:1]([C:3]1[N:8]=[C:7]([NH2:9])[CH:6]=[CH:5][N:4]=1)[CH3:2].[Cl:10][C:11]1[C:12]([CH3:21])=[C:13]([S:17](Cl)(=[O:19])=[O:18])[CH:14]=[CH:15][CH:16]=1>>[Cl:10][C:11]1[C:12]([CH3:21])=[C:13]([S:17]([NH:9][C:7]2[CH:6]=[CH:5][N:4]=[C:3]([CH2:1][CH3:2])[N:8]=2)(=[O:19])=[O:18])[CH:14]=[CH:15][CH:16]=1

Participants

3

Reactant 2

HCID 5227343-Chloro-2-methylbenzenesulfonyl chlorideHCID 139252962-Ethyl-4-pyrimidinamine

Product 1

HCID 116237683-Chloro-N-(2-ethyl-pyrimidin-4-yl)-2-methyl-benzenesulfonamide

Procedure

This compound was obtained according to example 2, step B] from 2-ethyl-pyrimidin-4-ylamine (0.25 g), and 3-chloro-2-methyl-benzenesulfonyl chloride (0.55 g) as a colorless solid (86 mg). MS (ESI−): 310.0 ([M−H]−).

Workup

  1. customThis compound was obtained

Sources & evidence

ORD record
ord-3b73d4d4d4ee41bfa2cbeea7f5c4bc2a
Source dataset
uspto-grants-2009_03
Patent number
US07507733B2

Reaction notes

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