反应详情

As described for example 112a, [1,2,3]triazol-2-yl-acetic acid ethyl ester in ethanol was reacted with hydrazine hydrate (2 equivalents) and the resulting mixture heated under reflux for 3 h. The mixture was cooled to rt and the precipitated product was filtered off and dried to afford the title compound as a white solid (yield: 68%). MS: m/e=141.1 [M]+.

1. temperaturethe resulting mixture heated
2. temperatureunder reflux for 3 h
3. filtrationthe precipitated product was filtered off
4. customdried