Hydrazine hydrate (1:1) → HCID 67549254, compound

Participants

Reaction Steps

As described for example 112a, (2-oxo-3-trifluoromethyl-2H-pyridin-1-yl)-acetic acid ethyl ester in ethanol was reacted with hydrazine hydrate (1.2 equivalents) at rt for 72 h. The mixture was concentrated and crystallized from ethanol/diisopropylether and the compound was obtained as a white solid (yield: 95%). MS: m/e=236.3 [M+H]+.

Provenance & Evidence