HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ethyl bromoacetate → HCID 67549574, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ethyl bromoacetate | HCID 7748 | — |
| Reactant | Heptane | HCID 8900 | — |
| Reactant | Potassium Carbonate | HCID 11430 | — |
| Reactant | 4-Methyl-2-pyrazolin-5-one | HCID 98935 | — |
| Solvent | Ethyl Acetate | HCID 8857 | — |
| Product | HCID 67549574 | HCID 67549574 | 16% |
Reaction Steps
As described for example 320a, 4-methyl-2-pyrazolin-5-one was reacted with ethyl bromoacetate and potassium carbonate. Extractive workup followed by chromatography (SiO2, heptane:ethyl acetate=100:0 to 50:50) afforded the title compound as a white solid (yield: 16%). MS: m/e=185.0 [M+H]+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507729B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-3aad6f459cfe4326ad8c19288ce80229 |
| Source note | uspto-grants-2009_03 |