HRID1786505

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID6916

Diethylcarbamoyl chloride

C5H10ClNO

结构：CC(C)N1CCC(Oc2ccc3c(c2)cc(C(=O)N2CCNCC2)n3C(C)C)CC1.Cl

HCID68565609

未命名化合物

PRODUCTS

生成物

结构：CCN(CC)C(=O)N1CCN(C(=O)c2cc3cc(OC4CCN(C(C)C)CC4)ccc3n2C(C)C)CC1

HCID68565435

未命名化合物

PROCEDURE

实验过程

The title compound was prepared in analogy to example 51, from [1-isopropyl-5-(1-isopropyl-piperidin-4-yloxy)-1H-indol-2-yl]-piperazin-1-yl-methanone hydrochloride and N,N-diethylcarbamoyl chloride. Off-white solid. MS (m/z): 512.5 (M+H)+.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-437296a80f494ff988b45523fbb7fb55
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07507736B2
来源说明: uspto-grants-2009_03

反应 SMILES

Cl.[CH:2]([N:5]1[C:13]2[C:8](=[CH:9][C:10]([O:14][CH:15]3[CH2:20][CH2:19][N:18]([CH:21]([CH3:23])[CH3:22])[CH2:17][CH2:16]3)=[CH:11][CH:12]=2)[CH:7]=[C:6]1[C:24]([N:26]1[CH2:31][CH2:30][NH:29][CH2:28][CH2:27]1)=[O:25])([CH3:4])[CH3:3].[CH2:32]([N:34]([CH2:38][CH3:39])[C:35](Cl)=[O:36])[CH3:33]>>[CH2:32]([N:34]([CH2:38][CH3:39])[C:35]([N:29]1[CH2:28][CH2:27][N:26]([C:24]([C:6]2[N:5]([CH:2]([CH3:3])[CH3:4])[C:13]3[C:8]([CH:7]=2)=[CH:9][C:10]([O:14][CH:15]2[CH2:20][CH2:19][N:18]([CH:21]([CH3:23])[CH3:22])[CH2:17][CH2:16]2)=[CH:11][CH:12]=3)=[O:25])[CH2:31][CH2:30]1)=[O:36])[CH3:33]