HuagongsheHuagongshe Chemistry Print Report · For research reference only
Methyl piperazine-1-carboxylate → 4-{5-[1-(2,2,2-Trifluoro-ethyl)-piperidin-4-yloxy]-1H-indole-2-carbonyl]-piperazine-1-carboxylic acid methyl ester
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Methyl piperazine-1-carboxylate | HCID 142729 | — |
| Reactant | 5-[1-(2,2,2-trifluoro-ethyl)-piperidin-4-yloxy]-1H-indole-2-carboxylic acid | HCID 68566812 | — |
| Product | 4-{5-[1-(2,2,2-Trifluoro-ethyl)-piperidin-4-yloxy]-1H-indole-2-carbonyl]-piperazine-1-carboxylic acid methyl ester | HCID 68566043 | — |
Reaction Steps
The title compound was prepared in analogy to example 40b), from 5-[1-(2,2,2-trifluoro-ethyl)-piperidin-4-yloxy]-1H-indole-2-carboxylic acid and methyl piperazine-1-carboxylate. Light yellow solid. MS (m/z): 469.3 (M+H)+.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507736B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-63c3ca63d3ed41baa0d4b9fe576da2ca |
| Source note | uspto-grants-2009_03 |