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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1786537Generated: October 29, 2026

HCID 131727367, compound → HCID 57597585, compound

https://huagongshe.com/reaction/1786537

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 131727367HCID 131727367—
CatalystPalladiumHCID 23938—
SolventMethanolHCID 887—
ProductHCID 57597585HCID 57597585—

Reaction Steps

To a solution of 6,6-Bis-(4-fluoro-phenyl)-hexanoic acid(1-benzoyl-pyrrolidin-3-yl)-methyl amide(1.0 g, 2.1 mmol in CH3OH (50 ml) was added Pd/C 20% (250 mg). The resulting slurry was hydrogenated at 50 psi for 24 hours. The catalyst was filtered through Celite and filtrate evaporated under reduced pressure to give 0.78 g of desired product.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07507760B2
Source datasetuspto-grants-2009_03
ORD IDord-dc32dab8144d4f6a9059963a3961787d
Source noteuspto-grants-2009_03