HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 131727367, compound → HCID 57597585, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 131727367 | HCID 131727367 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57597585 | HCID 57597585 | — |
Reaction Steps
To a solution of 6,6-Bis-(4-fluoro-phenyl)-hexanoic acid(1-benzoyl-pyrrolidin-3-yl)-methyl amide(1.0 g, 2.1 mmol in CH3OH (50 ml) was added Pd/C 20% (250 mg). The resulting slurry was hydrogenated at 50 psi for 24 hours. The catalyst was filtered through Celite and filtrate evaporated under reduced pressure to give 0.78 g of desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507760B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-dc32dab8144d4f6a9059963a3961787d |
| Source note | uspto-grants-2009_03 |