HuagongsheHuagongshe Chemistry Print Report · For research reference only
HCID 86599801, compound → HCID 57597558, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | HCID 86599801 | HCID 86599801 | — |
| Catalyst | Palladium | HCID 23938 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | HCID 57597558 | HCID 57597558 | 95.1% |
Reaction Steps
To a solution of (R)-2-[(1-benzoyl-pyrrolidin-3-yl)-methyl-amino]-N,N-diphenyl acetamide(0.68 g, 1.70 mmol) in CH3OH (30 ml) was added Pd/C 20% (170 mg). The resulting slurry was hydrogenated at 50 psi for 24 hours. The catalyst was filtered through Celite and filtrate evaporated under reduced pressure to give 0.5 g of desired product.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07507760B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-a1bf7b07a6e84b91be3f4ef0d347f994 |
| Source note | uspto-grants-2009_03 |