Propylamine → HCID 23114368, compound

HRID 1787302Notes

Reaction equation

HRID 1787302 reaction equation
[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[C:14]3[C:15]([CH3:30])=[C:16]([NH:21][C:22](=O)[O:23]CC(Cl)(Cl)Cl)[C:17]([CH3:20])=[C:18]([CH3:19])[C:13]=3[O:12][CH2:11]2)=[CH:6][CH:5]=1)([CH3:3])[CH3:2].[CH2:31]([NH2:34])[CH2:32][CH3:33]>CCCCCC.C(OCC)(=O)C>[CH:1]([C:4]1[CH:9]=[CH:8][C:7]([CH:10]2[C:14]3[C:15]([CH3:30])=[C:16]([NH:21][C:22]([NH:34][CH2:31][CH2:32][CH3:33])=[O:23])[C:17]([CH3:20])=[C:18]([CH3:19])[C:13]=3[O:12][CH2:11]2)=[CH:6][CH:5]=1)([CH3:2])[CH3:3]

Participants

4

Reactant 2

HCID 7852PropylamineHCID 86618058HCID 86618058, compound

Product 1

HCID 23114368HCID 23114368, compoundYield 53%

Reagents, catalysts & solvents 1

HCID 21226206Ethyl acetate hexaneSolvent

Procedure

Using 2,2,2-trichloroethyl (3-(4-isopropylphenyl)-4,6,7-trimethyl-2,3-dihydro-1-benzofuran-5-yl)carbamate obtained in Example 138 and 1-propylamine, the title compound was synthesized in the same manner as in Example 143. Yield: 53%. Melting point: 177-178° C. (hexane-ethyl acetate).

Sources & evidence

ORD record
ord-cc50d20058d24117b1fc031ff5e57a1b
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

Loading…