P-Cresol → HCID 23113854, compound

HRID 1787385Notes

Reaction equation

HRID 1787385 reaction equation
Br[C:2]1[C:10]2[O:9][C:8]([CH3:12])([CH3:11])[CH2:7][C:6]=2[C:5]([CH3:13])=[C:4]([NH:14][C:15](=[O:21])[CH2:16][C:17]([CH3:20])([CH3:19])[CH3:18])[C:3]=1[CH3:22].[CH3:23][C:24]1[CH:29]=[CH:28][C:27]([OH:30])=[CH:26][CH:25]=1>CCCCCC>[CH3:18][C:17]([CH3:20])([CH3:19])[CH2:16][C:15]([NH:14][C:4]1[C:3]([CH3:22])=[C:2]([O:30][C:27]2[CH:28]=[CH:29][C:24]([CH3:23])=[CH:25][CH:26]=2)[C:10]2[O:9][C:8]([CH3:12])([CH3:11])[CH2:7][C:6]=2[C:5]=1[CH3:13])=[O:21]

Participants

4

Reactant 2

HCID 2879P-CresolHCID 23114116HCID 23114116, compound

Product 1

HCID 23113854HCID 23113854, compoundYield 19%

Reagents, catalysts & solvents 1

HCID 8058HexaneSolvent

Procedure

Using N-(7-bromo-2,2,4,6-tetramethyl-2,3-dihydro-1-benzofuran-5-yl)-3,3-dimethylbutanamide obtained in Example 343 and 4-methylphenol, the title compound was synthesized in the same manner as in Example 344. Yield: 19%. Melting point: 182-184° C. (hexane).

Sources & evidence

ORD record
ord-d36096385fdc4bcfa8681acda7277228
Source dataset
uspto-grants-2009_03
Patent number
US07507841B2

Reaction notes

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