HuagongsheHuagongshe Chemistry Print Report · For research reference only
Water → 677341-61-6
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Water | HCID 962 | — |
| Reactant | Cyanogen Bromide | HCID 10476 | — |
| Reactant | 2-(1H-Imidazol-2-yl)aniline | HCID 15620500 | — |
| Solvent | Methanol | HCID 887 | — |
| Product | 677341-61-6 | HCID 66594113 | 61% |
Reaction Steps
To a solution of 2-(1H-imidazol-2-yl)aniline (0.06 g. 0.38 mmol) in methanol (3 ml) was added cyanogen bromide (0.05 g, 0.45 mmol). The resulting mixture was stirred at room temperature overnight. The reaction mixture was poured into water, and the resulting precipitate was collected by filtration, washed with acetone, and dried under reduced pressure to give imidazo[1,2-c]quinazolin-5-amine hydrobromide (0.06 g, 61% yield) as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511041B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-011aa2a49c6944ec819f2658840ab803 |
| Source note | uspto-grants-2009_03 |