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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787565Generated: October 30, 2026

Water → 677341-61-6

https://huagongshe.com/reaction/1787565

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantCyanogen BromideHCID 10476—
Reactant2-(1H-Imidazol-2-yl)anilineHCID 15620500—
SolventMethanolHCID 887—
Product677341-61-6HCID 6659411361%

Reaction Steps

To a solution of 2-(1H-imidazol-2-yl)aniline (0.06 g. 0.38 mmol) in methanol (3 ml) was added cyanogen bromide (0.05 g, 0.45 mmol). The resulting mixture was stirred at room temperature overnight. The reaction mixture was poured into water, and the resulting precipitate was collected by filtration, washed with acetone, and dried under reduced pressure to give imidazo[1,2-c]quinazolin-5-amine hydrobromide (0.06 g, 61% yield) as a white solid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511041B2
Source datasetuspto-grants-2009_03
ORD IDord-011aa2a49c6944ec819f2658840ab803
Source noteuspto-grants-2009_03