2-Amino-5-chloropyridine → (5-Chloro-pyridin-2-yl)-(2-methyl-[1,7]naphthyridin-8-yl)-amine

HRID 1787599Notes

Reaction equation

HRID 1787599 reaction equation
Cl[C:2]1[N:3]=[CH:4][CH:5]=[C:6]2[C:11]=1[N:10]=[C:9]([CH3:12])[CH:8]=[CH:7]2.[NH2:13][C:14]1[CH:19]=[CH:18][C:17]([Cl:20])=[CH:16][N:15]=1>>[Cl:20][C:17]1[CH:18]=[CH:19][C:14]([NH:13][C:2]2[N:3]=[CH:4][CH:5]=[C:6]3[C:11]=2[N:10]=[C:9]([CH3:12])[CH:8]=[CH:7]3)=[N:15][CH:16]=1

Participants

3

Reactant 2

HCID 661742-Amino-5-chloropyridineHCID 576003498-Chloro-2-methyl-1,7-naphthyridine

Product 1

HCID 16118553(5-Chloro-pyridin-2-yl)-(2-methyl-[1,7]naphthyridin-8-yl)-amine

Procedure

The title compound, MS: m/e=271.3 (M+H+), was prepared in accordance with the general method of example 1 from 8-chloro-2-methyl-[1,7]naphthyridine (Example E) and 2-amino-5-chloropyridine.

Sources & evidence

ORD record
ord-bbd668156b2645fb9ff12d4b73e59082
Source dataset
uspto-grants-2009_03
Patent number
US07511055B2

Reaction notes

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