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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787600Generated: October 28, 2026

2-Amino-5-fluoropyridine → (5-Fluoro-pyridin-2-yl)-(2-methyl-[1,7]naphthyridin-8-yl)-amine

https://huagongshe.com/reaction/1787600

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-5-fluoropyridineHCID 2737701—
Reactant8-Chloro-2-methyl-1,7-naphthyridineHCID 57600349—
Product(5-Fluoro-pyridin-2-yl)-(2-methyl-[1,7]naphthyridin-8-yl)-amineHCID 16118554—

Reaction Steps

The title compound, MS: m/e=255.3 (M+H+), was prepared in accordance with the general method of example 1 from 8-chloro-2-methyl-[1,7]naphthyridine (Example E) and 2-amino-5-fluoropyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511055B2
Source datasetuspto-grants-2009_03
ORD IDord-f3d4c0c1d8ae449d87cc74af3b913da1
Source noteuspto-grants-2009_03