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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787604Generated: October 30, 2026

2-Methyl-1,3-thiazol-4-amine → (2-Methyl-[1,7]naphthyridin-8-yl)-(2-methyl-thiazol-4-yl)-amine

https://huagongshe.com/reaction/1787604

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-1,3-thiazol-4-amineHCID 14772700—
Reactant8-Chloro-2-methyl-1,7-naphthyridineHCID 57600349—
Product(2-Methyl-[1,7]naphthyridin-8-yl)-(2-methyl-thiazol-4-yl)-amineHCID 16118557—

Reaction Steps

The title compound, MS: m/e=257.2 (M+H+), was prepared in accordance with the general method of example 1 from 8-chloro-2-methyl-[1,7]naphthyridine (Example E) and 4-amino-2-methylthiazole (Example F).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511055B2
Source datasetuspto-grants-2009_03
ORD IDord-8ed477f8a60747ec93439a256352e767
Source noteuspto-grants-2009_03