2-Amino-4-methylthiazole → HCID 16118690, compound

HRID 1787605Notes

Reaction equation

HRID 1787605 reaction equation
[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[C:5](OS(C(F)(F)F)(=O)=O)[N:6]=[CH:7][CH:8]=2)[N:3]=1.[NH2:20][C:21]1[S:22][CH:23]=[C:24]([CH3:26])[N:25]=1>>[Cl:1][C:2]1[CH:11]=[CH:10][C:9]2[C:4](=[C:5]([NH:20][C:21]3[S:22][CH:23]=[C:24]([CH3:26])[N:25]=3)[N:6]=[CH:7][CH:8]=2)[N:3]=1

Participants

3

Reactant 2

HCID 741432-Amino-4-methylthiazoleHCID 57600353HCID 57600353, compound

Product 1

HCID 16118690HCID 16118690, compound

Procedure

The title compound, MS: m/e=277 (M+H+), was prepared in accordance with the general method of example 1 from trifluoro-methanesulfonic acid 2-chloro-[1,7]naphthyridin-8-yl ester (Example G) and 2-amino-4-methylthiazole.

Sources & evidence

ORD record
ord-bb5254cd0daa47f9b18dffbad37835dc
Source dataset
uspto-grants-2009_03
Patent number
US07511055B2

Reaction notes

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