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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787606Generated: November 1, 2026

2-Methyl-1,3-thiazol-4-amine → 2-Chloro-N-(2-methyl-4-thiazolyl)-1,7-naphthyridin-8-amine

https://huagongshe.com/reaction/1787606

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Methyl-1,3-thiazol-4-amineHCID 14772700—
ReactantHCID 57600353HCID 57600353—
Product2-Chloro-N-(2-methyl-4-thiazolyl)-1,7-naphthyridin-8-amineHCID 16118691—

Reaction Steps

The title compound, MS: m/e=277.0/279.1 (M+H+), was prepared in accordance with the general method of example 1 from trifluoro-methanesulfonic acid 2-chloro-[1,7]naphthyridin-8-yl ester (Example G) and 4-amino-2-methylthiazole (Example F).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511055B2
Source datasetuspto-grants-2009_03
ORD IDord-f890bc82a5114a1087e119534befe52f
Source noteuspto-grants-2009_03