1,3-Dibromobenzene → 3-Benzyl-8-(3-bromo-phenyl)-3-aza-bicyclo[3.2.1]octan-8-ol
Reaction equation
[Br:1][c:2]1[cH:3][cH:4][cH:5][c:6]([Br:7])[cH:8]1.[CH2:14]([c:15]1[cH:16][cH:17][cH:18][cH:19][cH:20]1)[N:21]1[CH2:22][CH:23]2[CH2:24][CH2:25][CH:26]([CH2:27]1)[C:28]2=[O:29].[CH2:9]([Li:10])[CH2:11][CH2:12][CH3:13]>>[c:2]1([C:28]2([OH:29])[CH:23]3[CH2:22][N:21]([CH2:14][c:15]4[cH:16][cH:17][cH:18][cH:19][cH:20]4)[CH2:27][CH:26]2[CH2:25][CH2:24]3)[cH:3][cH:4][cH:5][c:6]([Br:7])[cH:8]1Participants
4
Sources & evidence
- ORD record
- ord-687a09e173f3491e85d14fc73d3cf665
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (6/10)
Reaction notes
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