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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787625Generated: October 29, 2026

2-Amino-4-methylthiazole → HCID 16116929, compound

https://huagongshe.com/reaction/1787625

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Amino-4-methylthiazoleHCID 74143—
Reactant2-Cyanopyridine-5-boronic acid pinacol esterHCID 16414188—
Reactant8-Chloro-5-iodo-2-methyl-[1,7]naphthyridineHCID 57600352—
ProductHCID 16116929HCID 16116929—

Reaction Steps

The title compound, MS: m/e=359.1 (M+H+), was prepared in accordance with the general method of example 15 step 1 and step 3 from 8-chloro-5-iodo-2-methyl-[1,7]naphthyridine (Example I), 2-cyanopyridine-5-boronic acid pinacol ester and 2-amino-4-methylthiazole.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511055B2
Source datasetuspto-grants-2009_03
ORD IDord-8ac3fdb2e11c45ecb858c06e97b2f356
Source noteuspto-grants-2009_03