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HRID1787846

反应详情

EQUATION

反应方程式

HRID 1787846 的结构方程式

REACTANTS

反应物

3
结构：[BH4-].[Na+]
HCID4311764

Sodium borohydride (Na(BH4))

H4BNa

结构：[Ca+2].[Cl-].[Cl-]
HCID5284359

未命名化合物

结构：COC(=O)c1cc(C(O)CNC(C)(C)CCn2cncn2)ccc1OCc1ccccc1
HCID68877359

未命名化合物

PRODUCTS

生成物

1
结构：CC(C)(CCn1cncn1)NCC(O)c1ccc(OCc2ccccc2)c(CO)c1
HCID68878113

未命名化合物

PROCEDURE

实验过程

7.6 g of methyl 2-benzyloxy-5-[2-[1,1-dimethyl-3-[1,2,4]triazol-1-yl-propylamino]-1-hydroxy-ethyl]-benzoate are reduced in an ethanolic calcium chloride solution with sodium borohydride as described for Example 1c. The product is obtained as a colourless oil after purification by column chromatography (CHCl3/MeOH/NH3=90/10/0.5). Yield: 6 g (84%).

WORKUP

后处理

  1. customThe product is obtained as a colourless oil
  2. customafter purification by column chromatography (CHCl3/MeOH/NH3=90/10/0.5)