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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787854Generated: October 27, 2026

1,1-Dimethyl-3-(5-methyl-3-p-tolyl-[1,2,4]triazol-1-yl)-propylamine → 4-{2-[1,1-Dimethyl-3-(5-methyl-3-p-tolyl-[1,2,4]triazol-1-yl)-propylamino]-1-hydroxy-ethyl}-2-hydroxymethyl-phenol

https://huagongshe.com/reaction/1787854

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1,1-Dimethyl-3-(5-methyl-3-p-tolyl-[1,2,4]triazol-1-yl)-propylamineHCID 59754201—
ReactantMethyl benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoateHCID 68858509—
Product4-{2-[1,1-Dimethyl-3-(5-methyl-3-p-tolyl-[1,2,4]triazol-1-yl)-propylamino]-1-hydroxy-ethyl}-2-hydroxymethyl-phenolHCID 57602516—

Reaction Steps

The compound is prepared analogously to the general working method A from 241 mg (0.7 mmol) of methyl 2-benzyloxy-5-(2-ethoxy-2-hydroxy-acetyl)-benzoate and 181 mg (0.7 mmol) of 1,1-dimethyl-3-(5-methyl-3-p-tolyl-[1,2,4]triazol-1-yl)-propylamine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511067B2
Source datasetuspto-grants-2009_03
ORD IDord-5e6f2fd3a3bf42e88505fcf3d36a1220
Source noteuspto-grants-2009_03