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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1787912Generated: October 30, 2026

Methyl 3-amino-2-thiophenecarboxylate → HCID 57602470, compound

https://huagongshe.com/reaction/1787912

Reaction equation

Participants

RoleNameHCIDCharge
ReactantMethyl 3-amino-2-thiophenecarboxylateHCID 89652—
ReactantHCID 57602489HCID 57602489—
ReactantHCID 86610258HCID 86610258—
ProductHCID 57602470HCID 5760247058%

Reaction Steps

Using methods substantially equivalent to those described in Example 12-C, methyl 3-[2-(1-tert-butoxy-carbonylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoylamino]-thiophene-2-carboxylate was prepared in a 58% yield from 2-(1-tert-butoxycarbonylpiperidin-4-yloxy)-4-(pyrrolidin-1-yl)benzoic acid and methyl 3-aminothiophene-2-carboxylate.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511066B2
Source datasetuspto-grants-2009_03
ORD IDord-ab34c9d7e1bb44e1bf823119269e3b8a
Source noteuspto-grants-2009_03