HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → 4-Amino-N-(1,1-dimethylethyl)benzenesulfonamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | N-[4-(tert-butylsulfamoyl)phenyl]acetamide | HCID 668309 | — |
| Solvent | Sodium Hydroxide | HCID 14798 | — |
| Product | 4-Amino-N-(1,1-dimethylethyl)benzenesulfonamide | HCID 832627 | — |
Reaction Steps
N-(1,1-Dimethylethyl)-4-(acetylamino)benzenesulfonamide (Example 11) is deprotected by saponification in 20% NaOH (5 mL), followed by neutralization with 10% HCl. The precipitate that is formed is collected by filtration and recrystallized from methanol/diethyl ether.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511133B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-ff145d030128435c8c79a13cc1baebb8 |
| Source note | uspto-grants-2009_03 |