Pyridinium chloride → HCID 57437985, compound

Participants

Reaction Conditions

Reaction Steps

A mixture of 46.14 g (0.125 mol) of 2-[5-(benzyloxy)-1H-indazol-3-yl]-1H-isoindole-1,3(2H)-dione and 143.35 g (1.24 mol) of piridine hydrochloride was heated at 180° C. for 1.5 hours. The resulting brown solution was cooled to 120° C. and slowly poured in a well stirred mixture of 800 ml of 0.5 N HCl. The precipitate was filtered off and dried: 32.26 g of product as yellow solid were obtained. Yield=92.4%.

Provenance & Evidence