反应详情

To a solution of the compound prepared in Example 2 (986 mg) in tetrahydrofuran (12 mL) was dropwise added 1-isocyanato-3,5-bis(trifluoromethyl)benzene (0.85 mL), and the mixture was stirred for 30 minutes. The reaction solution was concentrated. The residue was purified by column chromatography on silica gel (hexane:ethyl acetate=1:1) to give the compound of the present invention (1.413 g) having the following physical data.

1. concentrationThe reaction solution was concentrated
2. customThe residue was purified by column chromatography on silica gel (hexane:ethyl acetate=1:1)
3. customto give the compound of the present invention (1.413 g)