反应详情

温度

25 °C

4-Chlorophenol (4 g, 31.25 mmol) was added in portions to chlorosulfonic acid (10.3 mL, 156 mmol) while cooling in an ice bath. The resulting solution was stirred at 25° C. for 20 hrs. This was then added drop-wise to ice and water resulting in an emulsion. This was extracted with CHCl3, dried (Na2SO4) and concentrated in vacuo. Heptane was added and evaporated and replaced with cyclohexane. The resulting mixture was filtered and concentrated to give the title compound as an oil (2.16 g).

1. temperaturewhile cooling in an ice bath
2. extractionThis was extracted with CHCl3
3. dry with materialdried (Na2SO4)
4. concentrationconcentrated in vacuo
5. additionHeptane was added
6. customevaporated
7. filtrationThe resulting mixture was filtered
8. concentrationconcentrated