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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788421Generated: November 1, 2026

Sodium Hydroxide → HCID 5276162, compound

https://huagongshe.com/reaction/1788421

Reaction equation

Participants

RoleNameHCIDCharge
ReactantSodium HydroxideHCID 14798—
ReactantDimethyl glutamateHCID 93032—
ReactantHCID 11213026HCID 11213026—
ReactantHCID 57623685HCID 57623685—
ProductHCID 5276162HCID 527616215%

Reaction Steps

Compound 237 was synthesized from Compound 201 as described for Compound 235, using L-glutamic acid dimethylester in place of L-5-hydroxytryptophane. In the 3rd step the protected intermediate was treated with aqueous sodium hydroxide for a 15% yield of the title compound

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-bfe9ed1a60e440c4aca3ac6e6d1cc065
Source noteuspto-grants-2009_03