Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Fmoc-Cha-OH → 2-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Fmoc-Cha-OH | HCID 978326 | — |
| 반응물 | 3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid | HCID 5276167 | — |
| 생성물 | 2-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]acetic acid | HCID 5276168 | 48% |
반응 단계
The general procedure described for Compound 242 was used with Fmoc-Cha Wang resin (250 mg, 0.4 mmol/g), producing 29 mg of the title compound (48% yield). MS: 586.27 (M−H+) HPLC Procedure A, retention time=14.94 min.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07511145B2 |
| 출처 데이터셋 | uspto-grants-2009_03 |
| ORD ID | ord-e3f42ab515274d48aa98ec9b3327df67 |
| 출처 메모 | uspto-grants-2009_03 |