HuagongsheHuagongshe Chemistry Print Report · For research reference only
3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid → {[1-Cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1h-benzoimidazole-5-carbonyl]-amino}-acetic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3-Cyclohexyl-2-[[1-cyclohexyl-2-(2-phenylquinoxalin-6-yl)benzimidazole-5-carbonyl]amino]propanoic acid | HCID 5276167 | — |
| Reactant | (9H-Fluoren-9-yl)methyl 2-oxoethylcarbamate | HCID 10858926 | — |
| Product | {[1-Cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1h-benzoimidazole-5-carbonyl]-amino}-acetic acid | HCID 57603150 | 55% |
Reaction Steps
The general procedure described for Compound 242 was used with Fmoc-Gly Wang resin (125 mg, 0.8 mmol/g), producing 30 mg of the title compound (55% yield). MS: 504.21 (M−H+) HPLC Procedure A, retention time=12.32 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-0a38c25b623e4a459694e3d4280799ad |
| Source note | uspto-grants-2009_03 |