HCID 68919442, compound → HCID 68919304, compound

Participants

Reaction Steps

Compound 471b (500 mg, 1.4 mmol) was refluxed in a mixture of 15 mL dioxane and 15 mL 1M aqueous NaOH for 1 h then it was evaporated to dryness, the residue dissolved in 50 mL water and acidified with 1M HCl solution to pH 4. The precipitate was filtered off, washed four times with water and dried. Yield: 361 mg (75%).

Provenance & Evidence