HRID1788440

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID69714

1-(2-Hydroxy-5-methoxyphenyl)ethan-1-one

C9H10O3

结构：O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(C(=O)N5CCCC5)ccc4-c4ccc(Cl)cc4)ccc3c1)n2C1CCCCC1

HCID11181341

未命名化合物

PRODUCTS

生成物

结构：COc1ccc(-c2ccc(Cl)cc2)c(-c2ccc3cc(-c4nc5cc(C(=O)O)ccc5n4C4CCCCC4)ccc3n2)c1

HCID5275982

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in seven steps as described for Compound 204 except 2-hydroxy-5-methoxy acetophenone was used instead of Compound 18.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-b35501ea7ea84326a3153ec3757cfa04
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07511145B2
来源说明: uspto-grants-2009_03

反应 SMILES

[Cl:1][C:2]1[CH:48]=[CH:47][C:5]([C:6]2[C:11]([C:12]3[CH:21]=[CH:20][C:19]4[C:14](=[CH:15][CH:16]=[C:17]([C:22]5[N:26]([CH:27]6[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]6)[C:25]6[CH:33]=[CH:34][C:35]([C:37]([OH:39])=[O:38])=[CH:36][C:24]=6[N:23]=5)[CH:18]=4)[N:13]=3)=[CH:10][C:9](C(N3CCCC3)=O)=[CH:8][CH:7]=2)=[CH:4][CH:3]=1.C[C:50](C1C=C(OC)C=CC=1O)=[O:51]>>[Cl:1][C:2]1[CH:3]=[CH:4][C:5]([C:6]2[C:11]([C:12]3[CH:21]=[CH:20][C:19]4[C:14](=[CH:15][CH:16]=[C:17]([C:22]5[N:26]([CH:27]6[CH2:32][CH2:31][CH2:30][CH2:29][CH2:28]6)[C:25]6[CH:33]=[CH:34][C:35]([C:37]([OH:39])=[O:38])=[CH:36][C:24]=6[N:23]=5)[CH:18]=4)[N:13]=3)=[CH:10][C:9]([O:51][CH3:50])=[CH:8][CH:7]=2)=[CH:47][CH:48]=1