1-(2-Hydroxy-5-methoxyphenyl)ethan-1-one → 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-cyclohexyl-benzimidazole-5-carboxylic acid

Participants

Role	Name	HCID	Charge
Reactant	1-(2-Hydroxy-5-methoxyphenyl)ethan-1-one	HCID 69714	—
Reactant	2-{2-[4'-Chloro-4-(pyrrolidine-1-carbonyl)-biphen-2-yl]-quinolin-6-yl}-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid	HCID 11181341	—
Product	2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-cyclohexyl-benzimidazole-5-carboxylic acid	HCID 5275982	—

Reaction Steps

The title compound was synthesized in seven steps as described for Compound 204 except 2-hydroxy-5-methoxy acetophenone was used instead of Compound 18.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07511145B2
Source dataset	uspto-grants-2009_03
ORD ID	ord-b35501ea7ea84326a3153ec3757cfa04
Source note	uspto-grants-2009_03