HuagongsheHuagongshe Chemistry Print Report · For research reference only
5-Amino-1-naphthol → 1-Cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1H-benzoimidazole-5-carboxylic Acid (5-hydroxy-naphthalen-1-yl)-amide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 5-Amino-1-naphthol | HCID 65746 | — |
| Reactant | 1-cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1H-benzoimidazole-5-carboxylic Acid morpholin-4-ylamide | HCID 57603045 | — |
| Product | 1-Cyclohexyl-2-(2-phenyl-quinoxalin-6-yl)-1H-benzoimidazole-5-carboxylic Acid (5-hydroxy-naphthalen-1-yl)-amide | HCID 136096456 | 25% |
Reaction Steps
The general procedure described for Compound 574 was used with 5-amino-naphthalen-1-ol (15.9 mg), producing 7 mg of the title compound (25% yield). MS: 590.24 (M+H+) HPLC Procedure A, retention time=15.26 min.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-6d15d8fd54c041dc9ea09e3f50429660 |
| Source note | uspto-grants-2009_03 |