HRID1788471

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID92249

2H-1-Benzopyran-2-one, 7-amino-4-methyl-

C10H9NO2

结构：O=C(NN1CCOCC1)c1ccc2c(c1)nc(-c1ccc3nc(-c4ccccc4)cnc3c1)n2C1CCCCC1

HCID57603045

未命名化合物

PRODUCTS

生成物

结构：Cc1cc(=O)oc2cc(NC(=O)c3ccc4c(c3)nc(-c3ccc5nc(-c6ccccc6)cnc5c3)n4C3CCCCC3)ccc12

HCID57603151

未命名化合物

收率 27%

PROCEDURE

实验过程

The general procedure described for Compound 574 was used with 7-Amino-4-methyl-chromen-2-one (17.5 mg), producing 8 mg of the title compound (27% yield). MS: 606.29 (M+H+) HPLC Procedure A, retention time=19.22 min.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-4fd734490f3241b4926853d768dbdc08
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07511145B2
来源说明: uspto-grants-2009_03

反应 SMILES

N1([NH:7][C:8]([C:10]2[CH:40]=[CH:39][C:13]3[N:14]([CH:33]4[CH2:38][CH2:37][CH2:36][CH2:35][CH2:34]4)[C:15]([C:17]4[CH:18]=[C:19]5[C:24](=[CH:25][CH:26]=4)[N:23]=[C:22]([C:27]4[CH:32]=[CH:31][CH:30]=[CH:29][CH:28]=4)[CH:21]=[N:20]5)=[N:16][C:12]=3[CH:11]=2)=[O:9])CCOCC1.N[C:42]1[CH:51]=[C:50]2[C:45]([C:46]([CH3:53])=[CH:47][C:48](=[O:52])[O:49]2)=[CH:44][CH:43]=1>>[CH3:53][C:46]1[C:45]2[C:50](=[CH:51][C:42]([NH:7][C:8]([C:10]3[CH:40]=[CH:39][C:13]4[N:14]([CH:33]5[CH2:34][CH2:35][CH2:36][CH2:37][CH2:38]5)[C:15]([C:17]5[CH:18]=[C:19]6[C:24](=[CH:25][CH:26]=5)[N:23]=[C:22]([C:27]5[CH:28]=[CH:29][CH:30]=[CH:31][CH:32]=5)[CH:21]=[N:20]6)=[N:16][C:12]=4[CH:11]=3)=[O:9])=[CH:43][CH:44]=2)[O:49][C:48](=[O:52])[CH:47]=1