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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788500Generated: November 4, 2026

Potassium Hydroxide → HCID 5276017, compound

https://huagongshe.com/reaction/1788500

Reaction equation

Participants

RoleNameHCIDCharge
ReactantPotassium HydroxideHCID 14797—
Reactant1-(7-Bromo-5-Methoxy-1-Benzofuran-2-Yl)-1-EthanoneHCID 2764520—
Reactant2-[2-(5-Bromo-2-hydroxy-phenyl)-6-quinolyl]-1-cyclohexyl-benzimidazole-5-carboxylic acidHCID 5275980—
SolventEthanolHCID 702—
ProductHCID 5276017HCID 527601717%

Reaction Steps

Following the procedure and workup for Compound 354, Compound 354e (100 mg, 0.256 mmol) was reacted with 1-(7-bromo-5-methoxy-benzofuran-2-yl)-ethanone (0.256 mmol) in ethanol (2 mL) using 10% w/v KOH in ethanol (506 μL, 0.64 mmol) to produce the title compound, 17% yield).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-daddd1a164d64e08853823a139fc8a8c
Source noteuspto-grants-2009_03