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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788560Generated: October 30, 2026

4-Chloro-3-nitrobenzoic acid → 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-isopentyl-benzimidazole-5-carboxylic acid

https://huagongshe.com/reaction/1788560

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-Chloro-3-nitrobenzoic acidHCID 7320—
ReactantIsoamylamineHCID 7894—
Reactant2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-ethyl-benzimidazole-5-carboxylic acidHCID 5276184—
Product2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-isopentyl-benzimidazole-5-carboxylic acidHCID 5276182—

Reaction Steps

The title compound was prepared from Resin 534a and isoamylamine according to the procedure described in the preparation Compound 534.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-8e2b3249e2694788abdfe82fec322288
Source noteuspto-grants-2009_03