4-Chloro-3-nitrobenzoic acid → 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-isopentyl-benzimidazole-5-carboxylic acid

HRID 1788560Notes

Reaction equation

HRID 1788560 reaction equation
Cl[C:2]1[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=1[N+:11]([O-])=O.C(N)CC(C)C.[Cl:20][C:21]1[CH:58]=[CH:57][C:24]([C:25]2[C:30]([C:31]3[CH:40]=[CH:39][C:38]4[C:33](=[CH:34][CH:35]=[C:36]([C:41]5N(CC)C6C=[CH:49][C:50]([C:52](O)=O)=[CH:51][C:43]=6[N:42]=5)[CH:37]=4)[N:32]=3)=[CH:29][C:28]([O:55][CH3:56])=[CH:27][CH:26]=2)=[CH:23][CH:22]=1>>[Cl:20][C:21]1[CH:58]=[CH:57][C:24]([C:25]2[C:30]([C:31]3[CH:40]=[CH:39][C:38]4[C:33](=[CH:34][CH:35]=[C:36]([C:41]5[N:42]([CH2:43][CH2:51][CH:50]([CH3:52])[CH3:49])[C:2]6[CH:10]=[CH:9][C:5]([C:6]([OH:8])=[O:7])=[CH:4][C:3]=6[N:11]=5)[CH:37]=4)[N:32]=3)=[CH:29][C:28]([O:55][CH3:56])=[CH:27][CH:26]=2)=[CH:23][CH:22]=1

Participants

4

Procedure

The title compound was prepared from Resin 534a and isoamylamine according to the procedure described in the preparation Compound 534.

Sources & evidence

ORD record
ord-8e2b3249e2694788abdfe82fec322288
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Reaction notes

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