HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Chloro-3-nitrobenzoic acid → 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-(4-methylcyclohexyl)benzimidazole-5-carboxylic acid
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Chloro-3-nitrobenzoic acid | HCID 7320 | — |
| Reactant | 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-ethyl-benzimidazole-5-carboxylic acid | HCID 5276184 | — |
| Reactant | HCID 178461305 | HCID 178461305 | — |
| Product | 2-[2-[2-(4-Chlorophenyl)-5-methoxy-phenyl]-6-quinolyl]-1-(4-methylcyclohexyl)benzimidazole-5-carboxylic acid | HCID 5276131 | — |
Reaction Steps
The title compound was prepared from Resin 534a and a mixture of cis and trans 4-methylcyclohexyl-amine according to the procedure described in the preparation of Compound 534.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-85aae62cdf464e669bee6474f376901c |
| Source note | uspto-grants-2009_03 |