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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788577Generated: October 31, 2026

1H-Imidazole-1-propanamine → HCID 5276071, compound

https://huagongshe.com/reaction/1788577

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1H-Imidazole-1-propanamineHCID 78736—
Reactant1-Cyclohexyl-2-[4-(dimethylamino)-2-phenyl-6-quinolyl]benzimidazole-5-carboxylic acidHCID 5276100—
ReactantHCID 68924249HCID 68924249—
ProductHCID 5276071HCID 5276071—

Reaction Steps

In this reaction 102 mg (0.2 mmol) of crude 2-(4-chloro-2-phenyl-quinolin-6-yl)-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid ethyl ester were used in the same reaction sequence as that used for Compound 481. The nucleophile used was 3-imidazol-1-yl-propylamine. Yield: 31 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-6c72001d47fa4633b55549ce9ad7c27d
Source noteuspto-grants-2009_03