HRID1788588

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7410

Acetophenone

C8H8O

HCID69907

2-Propanone, 1,1-diphenyl-

C15H14O

结构：O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(-c4cc(C(=O)N5CCCC5)ccc4-c4ccc(Cl)cc4)ccc3c1)n2C1CCCCC1

HCID11181341

未命名化合物

结构：CCOC(=O)c1ccc(NC2CCCCC2)c(NC(=O)c2ccc3nc(-c4cc(C(=O)N5CCCC5)ccc4-c4ccc(Cl)cc4)ccc3c2)c1

HCID57603089

未命名化合物

PRODUCTS

生成物

结构：O=C(O)c1ccc2c(c1)nc(-c1ccc3nc(C(c4ccccc4)c4ccccc4)ccc3c1)n2C1CCCCC1

HCID5276076

未命名化合物

PROCEDURE

实验过程

The title compound was synthesized in four steps as described for Compound 13, Compound 25, Compound 27, Q=ethyl and Compound 204, respectively, except 1,1-diphenylacetone was used in the first step, instead of acetophenone.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-7165482d1b544f339b673f77c011c5ae
来源数据集: uspto-grants-2009_03
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07511145B2
来源说明: uspto-grants-2009_03

反应 SMILES

C(OC(=O)C1C=CC(NC2CCCCC2)=C(NC(C2C=C3C(=CC=2)N=[C:26]([C:31]2[C:36]([C:37]4[CH:42]=[CH:41][C:40](Cl)=[CH:39][CH:38]=4)=[CH:35][CH:34]=[C:33](C(N4CCCC4)=O)[CH:32]=2)C=C3)=O)C=1)C.ClC1C=CC(C2C([C:63]3[CH:72]=[CH:71][C:70]4[C:65](=[CH:66][CH:67]=[C:68]([C:73]5[N:77]([CH:78]6[CH2:83][CH2:82][CH2:81][CH2:80][CH2:79]6)[C:76]6[CH:84]=[CH:85][C:86]([C:88]([OH:90])=[O:89])=[CH:87][C:75]=6[N:74]=5)[CH:69]=4)[N:64]=3)=CC(C(N3CCCC3)=O)=CC=2)=CC=1.C1(C(C2C=CC=CC=2)C(C)=O)C=CC=CC=1.C(C1C=CC=CC=1)(=O)C>>[CH:36]([C:63]1[CH:72]=[CH:71][C:70]2[C:65](=[CH:66][CH:67]=[C:68]([C:73]3[N:77]([CH:78]4[CH2:83][CH2:82][CH2:81][CH2:80][CH2:79]4)[C:76]4[CH:84]=[CH:85][C:86]([C:88]([OH:90])=[O:89])=[CH:87][C:75]=4[N:74]=3)[CH:69]=2)[N:64]=1)([C:31]1[CH:26]=[CH:35][CH:34]=[CH:33][CH:32]=1)[C:37]1[CH:38]=[CH:39][CH:40]=[CH:41][CH:42]=1