HuagongsheHuagongshe Chemistry Print Report · For research reference only
Potassium Hydroxide → HCID 5276133, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Potassium Hydroxide | HCID 14797 | — |
| Reactant | 2-[2-(5-Bromo-2-hydroxy-phenyl)-6-quinolyl]-1-cyclohexyl-benzimidazole-5-carboxylic acid | HCID 5275980 | — |
| Reactant | HCID 68926336 | HCID 68926336 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | HCID 5276133 | HCID 5276133 | 21% |
Reaction Steps
Following the procedure and workup for Compound 354, Compound 354e (86 mg, 0.22 mmol) was reacted with Compound 545a (50 mg, 0.22 mmol) in ethanol (3 mL) using 10% w/v KOH in Ethanol (436 μL, 0.66 mmol) to produce the title compound (26 mg, 21% yield).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07511145B2 |
| Source dataset | uspto-grants-2009_03 |
| ORD ID | ord-d561aa8de7184e83af868602a51ae444 |
| Source note | uspto-grants-2009_03 |