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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1788610Generated: November 4, 2026

Hydrazine → HCID 5276085, compound

https://huagongshe.com/reaction/1788610

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrazineHCID 9321—
Reactant1-Cyclohexyl-2-[4-(dimethylamino)-2-phenyl-6-quinolyl]benzimidazole-5-carboxylic acidHCID 5276100—
ReactantHCID 68924249HCID 68924249—
ProductHCID 5276085HCID 5276085—

Reaction Steps

In this reaction 102 mg (0.2 mmol) of crude 2-(4-chloro-2-phenyl-quinolin-6-yl)-1-cyclohexyl-1H-benzoimidazole-5-carboxylic acid ethyl ester was reacted with hydrazine as the nucleophile as described for the preparation of Compound 481. Yield: 3.7 mg.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07511145B2
Source datasetuspto-grants-2009_03
ORD IDord-7dd4b2a4ef5644a1bfb4229c4d0aa572
Source noteuspto-grants-2009_03