Hydrochloric Acid → HCID 12909402, compound

HRID 1788612Notes

Reaction equation

HRID 1788612 reaction equation
[Cl:1][C:2]1[C:10]([N+:11]([O-:13])=[O:12])=[CH:9][CH:8]=[CH:7][C:3]=1[C:4]([OH:6])=[O:5].Cl.[CH3:15][CH2:16]O>>[CH2:15]([O:5][C:4](=[O:6])[C:3]1[CH:7]=[CH:8][CH:9]=[C:10]([N+:11]([O-:13])=[O:12])[C:2]=1[Cl:1])[CH3:16]

Participants

4

Reactant 3

HCID 313Hydrochloric AcidHCID 702EthanolHCID 198702-Chloro-3-nitrobenzoic acid

Product 1

HCID 12909402HCID 12909402, compound

Procedure

To a solution of 2-chloro-3-nitrobenzoic acid (0.85 g, 4.22 mmol) in anhydrous EtOH (50 mL) was bubbled with dry hydrogen chloride for 2 h at room temperature and the mixture was then stirred at room temperate overnight. After evaporation of solvent, water (100 mL) was added and the precipitates were collected by filtration and dried to give 2-chloro-3-nitro-benzoic acid ethyl ester.

Workup

  1. customAfter evaporation of solvent, water (100 mL)
  2. additionwas added
  3. filtrationthe precipitates were collected by filtration
  4. customdried

Sources & evidence

ORD record
ord-bb2c15bd615d4f6794cd3558a526f54a
Source dataset
uspto-grants-2009_03
Patent number
US07511145B2

Reaction notes

Loading…