2,4-Dinitrophenylacetic acid → HCID 70444843, compound

HRID 1788621Notes

Reaction equation

HRID 1788621 reaction equation
[N+:1]([C:4]1[CH:9]=[C:8]([N+:10]([O-])=O)[CH:7]=[CH:6][C:5]=1[CH2:13][C:14]([OH:16])=[O:15])([O-])=O.[H][H].C(=O)([O-])O.[Na+:23]>O.[Pd]>[Na+:23].[NH2:1][C:4]1[CH:9]=[C:8]([NH2:10])[CH:7]=[CH:6][C:5]=1[CH2:13][C:14]([O-:16])=[O:15]

Participants

6

Reactant 3

HCID 2215132,4-Dinitrophenylacetic acidHCID 516892Sodium BicarbonateHCID 178418361HCID 178418361, compound

Product 1

HCID 70444843HCID 70444843, compoundYield 84.1%

Reagents, catalysts & solvents 2

HCID 23938PalladiumCatalystHCID 962WaterSolvent

Procedure

Five grams of 2,4-dinitrophenylacetic acid were dissolved in a solution of 1.9 gm of sodium hydrogen carbonate in 200 ml water and reduced with hydrogen in the presence of 0.3 gm of palladium on charcoal at room temperature. After completion of the uptake of hydrogen, the catalyst was filtered off, and the filtrate was evaporated in a rotary evaporator at a bath temperature of 30° C. maximum. An amount of 3.5 gm of 2,4-diaminophenylacetic acid sodium salt was obtained.

Workup

  1. filtrationAfter completion of the uptake of hydrogen, the catalyst was filtered off
  2. customthe filtrate was evaporated in a rotary evaporator at a bath temperature of 30° C. maximum

Sources & evidence

ORD record
ord-bb937fb985da4e238ffa165721bf85a6
Source dataset
uspto-grants-1987_08
Patent number
US04684371

Reaction notes

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